Neuroscience Databases: A Practical Guide Chapter 19 Federation of Brain Data through Knowledge-guided Mediation

A Model-Based Mediator System for Scientific Data Management

A database mediator system combines information from multiple existing source databases and creates a new virtual, mediated database that comprises the integrated entities and their relationships. When mediating scientific data, the technically challenging problem of mediator query processing is further complicated by the complexity of the source data and the relationships between them. In part...

Federation of Brain Data through Knowledge-guided Mediation

In this chapter, we describe a data integration framework for multi-resolution data and some of the tools we have created for achieving integration of distributed data sources. The chapter is divided into two parts. In the first part, we describe a recently developed database for high resolution 3D data on cell structure and protein localization, the Cell Centered Database or CCDB. In the secon...

From Molecules to Brains: Navigating through Multi-resolution Imaging Data Using Knowledge-Guided Mediation

CT-guided laser probe for ablation of brain tumors

In this study, 22 patients (15-75 years old) were selected and transferred to CT scan for tumor ablation. For ablations, after prep and drep under the local anesthesia and mild sedation in proper position, small incision made and special needle inserted and guided by proper direction to the core of the tumor. Then, laser probe inserted through the needle and laser energy delivered. Although we ...

Grid-wide neuroimaging data federation in the context of the NeuroLOG project

Grid technologies are appealing to deal with the challenges raised by computational neurosciences and support multi-centric brain studies. However, core grids middleware hardly cope with the complex neuroimaging data representation and multi-layer data federation needs. Moreover, legacy neuroscience environments need to be preserved and cannot be simply superseded by grid services. This paper d...